Benzylideneacetone → HCID 19862112, compound

HRID 1165538Notes

Reaction equation

HRID 1165538 reaction equation
[C:1]([N:5]([CH2:10][CH:11]([OH:13])[CH3:12])[CH2:6][CH:7](O)[CH3:8])([CH3:4])([CH3:3])[CH3:2].C1(/C=C/C(=O)C)C=CC=CC=1>>[C:1]([N:5]1[CH:6]=[C:7]([CH3:8])[O:13][CH:11]([CH3:12])[CH2:10]1)([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 637759BenzylideneacetoneHCID 13930825N-t-butyl-bis-(2-hydroxypropyl)amine

Product 1

HCID 19862112HCID 19862112, compoundYield 56%

Procedure

N-t-butyl-bis-(2-hydroxypropyl)amine (60g, 0.32 mol) and trans-4-phenyl-3-buten-2-one (85g 10.58 mole) were subjected to a reaction as described in Example 1 above, except that the reaction temperature wa 220° C. A 56% yield of 3,4-dihydro-4-t-butyl-2,6-dimethyl-2H-1,4-oxazine was obtained.

Workup

  1. customwa 220° C

Sources & evidence

ORD record
ord-76d2dbd6f4ef4824a33b5a62e9ef757a
Source dataset
uspto-grants-1990_03
Patent number
US04910303

Reaction notes

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