Methanol → HCID 14676894, compound

Participants

Reaction Steps

A solution of 4-methylaminomethyl-5-ethyl-2,3,4,5-tetrahydrothiopyrano[3,2-b]indole (1.3 g) in methanol (30 ml) is mixed with an aqueous solution (10 ml) of sodium periodide (1.12 g) and kept at room temperature for 5 hours. The precipitate is filtered off and the filtrate is condensed. The residue is dissolved in methylene chloride, washed with water, dried and evaporated to give the title compound (1.28 g) as an oil: Yield 92.8%.

Provenance & Evidence