Hydrazine hydrate (1:1) → HCID 178462867, compound

Participants

Reaction Steps

A mixture of 6-chloro-5-cyano-1,3-diethylpyrimidine-2,4(1H, 3H)-dione(5 g) and hydrazine monohydrate (2.2 ml) in methanol (220 ml) was stirred for 10 minutes at room temperature. The reaction mixture was concentrated to dryness under reduced pressure, and the concentrate was crystallized from aqueous methanol to obtain colorless needles(4.3 g), m.p. 246°-248° C.

Provenance & Evidence