Hexane → HCID 178448715, compound

HRID 1165781Notes

Reaction equation

HRID 1165781 reaction equation
ClN1C(=O)CCC1=O.[CH2:9]([N:13]1[C:18]([NH:19][NH:20][C:21]([NH:23][CH2:24][C:25]([O:27][CH2:28][CH3:29])=[O:26])=S)=[CH:17][C:16](=[O:30])[N:15]([CH2:31][CH2:32][CH3:33])[C:14]1=[O:34])[CH2:10][CH2:11][CH3:12].CCCCCC>C(Cl)(Cl)Cl>[CH2:9]([N:13]1[C:18]2[NH:19][N:20]=[C:21]([NH:23][CH2:24][C:25]([O:27][CH2:28][CH3:29])=[O:26])[C:17]=2[C:16](=[O:30])[N:15]([CH2:31][CH2:32][CH3:33])[C:14]1=[O:34])[CH2:10][CH2:11][CH3:12]

Participants

5

Reactant 3

HCID 8058HexaneHCID 31398ChlorosuccinimideHCID 14838133HCID 14838133, compound

Product 1

HCID 178448715HCID 178448715, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To a stirred suspension of N-chlorosuccinimide (6.5 g) in chloroform (80 ml) was added in portions 1-butyl-6-(4-ethoxycarbonylmethylthiosemicarbazido)-3-propylpyrimidine-2,4(1H,3H)-dione (18 g) under ice-cooling. The mixture was stirred for one hour, followed by addition of hexane (200 ml) to give an insoluble product. The insoluble product was filtered off.

Workup

  1. temperaturecooling
  2. customto give an insoluble product
  3. filtrationThe insoluble product was filtered off

Sources & evidence

ORD record
ord-dae783762c134bbea4c89a8f0281e585
Source dataset
uspto-grants-1990_03
Patent number
US04912104

Reaction notes

Loading…