Methyl iodide → HCID 19860964, compound

HRID 1165792Notes

Reaction equation

HRID 1165792 reaction equation
[ClH:1].[N:2]1([CH2:7][CH:8]([N:10]2[C:23]3[CH:22]=[C:21]([C:24]([NH2:26])=[NH:25])[CH:20]=[CH:19][C:18]=3[S:17][C:16]3[C:11]2=[CH:12][CH:13]=[CH:14][CH:15]=3)[CH3:9])[CH2:6][CH2:5][CH2:4][CH2:3]1.C[I:28]>CN(C)C=O>[ClH:1].[I-:28].[NH+:2]1([CH2:7][CH:8]([N:10]2[C:23]3[CH:22]=[C:21]([C:24]([NH2:26])=[NH:25])[CH:20]=[CH:19][C:18]=3[S:17][C:16]3[C:11]2=[CH:12][CH:13]=[CH:14][CH:15]=3)[CH3:9])[CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 14502148HCID 14502148, compound

Product 1

HCID 19860964HCID 19860964, compoundYield 71.5%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In manner analogous to that described in Example 9 (sic), but starting with D series 10-[1-(1-pyrrolidinyl)-2-propyl]-2-phenothiazinecarboxamidine hydrochloride (2 g) in dimethylformamide (20 cc) and with methyl iodide (0.75 g), D series 10-[1-(1-pyrrolidinio)-2-propyl]-2-phenothiazinecarboxamidine iodide hydrochloride (1.9 g) is obtained in the form of a yellow powder.

Sources & evidence

ORD record
ord-8557b64ba86a4041bfa5122aa8803afd
Source dataset
uspto-grants-1990_03
Patent number
US04912105

Reaction notes

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