Hydrochloric Acid → HCID 13869731, compound

HRID 1165867Notes

Reaction equation

HRID 1165867 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[N:7]([CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:5])[CH3:2].[ClH:22]>CCOCC>[ClH:22].[CH2:1]([O:3][C:4]([CH:6]1[CH2:14][C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[N:7]1[CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 140166Indole-2-carboxylic acid, 1-benzyl-, ethyl ester

Product 1

HCID 13869731HCID 13869731, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Ethyl-1-benzylindole carboxylate is reduced as in the above example 3. The obtained oil is dissolved in ether and ethanolic hydrogen chloride is added to yield ethyl-1-benzyl-2,3-dihydroindole-carboxylate hydrochloride, m.p. 123°-124° C.

Sources & evidence

ORD record
ord-dc2cb3d396474893be6d055a28c516d4
Source dataset
uspto-grants-1990_03
Patent number
US04912125

Reaction notes

Loading…