Isopropanol → HCID 14515742, compound

HRID 1165892Notes

Reaction equation

[C:1]([C:4]1[C:13]2[C:7]([CH:8]=[CH:9][CH:10]=[C:11]([CH:14]([CH3:16])[CH3:15])[CH:12]=2)=[C:6]([CH2:17][CH3:18])[CH:5]=1)([OH:3])=[O:2].[CH:19](O)([CH3:21])[CH3:20]>>[CH:19]([O:2][C:1]([C:4]1[C:13]2[C:7]([CH:8]=[CH:9][CH:10]=[C:11]([CH:14]([CH3:15])[CH3:16])[CH:12]=2)=[C:6]([CH2:17][CH3:18])[CH:5]=1)=[O:3])([CH3:21])[CH3:20]

Participants

Reactant 2

HCID 3776Isopropanol

HCID 14515740HCID 14515740, compound

Product 1

HCID 14515742HCID 14515742, compound

Procedure

The acid chloride derivative (12) was produced in the same manner as in the synthesis of the above-mentioned 1-ethoxycarbonyl-3-ethyl-7-isoproylazulene (13) using 1-carboxy-3-ethyl-7-isopropylazulene (11) (1.21 g) as a starting material. Isopropanol was employed in place of the ethanol under the same reaction conditions and treatment as above to obtain the product (14) in a dark purple crystalline form, at a yield of 1.34 g (94.2%), having a melting point of 69° to 71° C.

Sources & evidence

ORD record: ord-7bb724b4a47e47b0b8c75cab1bf58d63
Source dataset: uspto-grants-1990_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04912134

Reaction notes

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