4-Chlorophenyl Isocyanate → 3-((((4-Chlorophenyl)amino)carbonyl)amino)-5-(2-fluorophenyl)-2,3-dihydro-2-oxo-1H-1,4-benzodiazepin-1-acetic acid ethyl ester
Reaction equation
[Cl:27][c:28]1[cH:29][cH:30][c:31]([N:34]=[C:35]=[O:36])[cH:32][cH:33]1.[NH2:1][CH:2]1[C:3](=[O:26])[N:4]([CH2:20][C:21](=[O:22])[O:23][CH2:24][CH3:25])[c:5]2[c:6]([cH:16][cH:17][cH:18][cH:19]2)[C:7]([c:9]2[c:10]([F:15])[cH:11][cH:12][cH:13][cH:14]2)=[N:8]1.[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[NH:1]([CH:2]1[C:3](=[O:26])[N:4]([CH2:20][C:21](=[O:22])[O:23][CH2:24][CH3:25])[c:5]2[c:6]([cH:16][cH:17][cH:18][cH:19]2)[C:7]([c:9]2[c:10]([F:15])[cH:11][cH:12][cH:13][cH:14]2)=[N:8]1)[C:35]([NH:34][c:31]1[cH:30][cH:29][c:28]([Cl:27])[cH:33][cH:32]1)=[O:36]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-e45136f53b27436e99b451897a1807f8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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