Sodium ion → 5'-methyl-1'-{[5-(trifluoromethyl)-2-furyl]methyl}spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

HRID 116606Notes

Reaction equation

HRID 116606 reaction equation
[Br:25][CH2:26][c:27]1[o:28][c:29]([C:32]([F:33])([F:34])[F:35])[cH:30][cH:31]1.[CH3:36][N:37]([CH3:38])[CH:39]=[O:40].[CH3:3][c:4]1[cH:5][c:6]2[c:7]([cH:8][cH:9]1)[NH:10][C:11](=[O:24])[C:12]21[CH2:13][O:14][c:15]2[c:16]1[cH:17][c:18]1[c:19]([cH:23]2)[O:20][CH2:21][O:22]1.[H-:1].[Na+:2]>>[CH3:3][c:4]1[cH:5][c:6]2[c:7]([cH:8][cH:9]1)[N:10]([CH2:26][c:27]1[o:28][c:29]([C:32]([F:33])([F:34])[F:35])[cH:30][cH:31]1)[C:11](=[O:24])[C:12]21[CH2:13][O:14][c:15]2[c:16]1[cH:17][c:18]1[c:19]([cH:23]2)[O:20][CH2:21][O:22]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 27946052-(Bromomethyl)-5-(trifluoromethyl)furanHCID 592634415'-methylspiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

Product 1

HCID 592633615'-methyl-1'-{[5-(trifluoromethyl)-2-furyl]methyl}spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

Sources & evidence

ORD record
ord-f346fe25234f48aaae645d7947f63075
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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