Dimethyl Sulfoxide → (+/-)-3-[7-[3-(2-diethylamino-ethyl)-phenylamino]-3-(4-methoxy-phenyl)-4-methyl-2-oxo-3,4-dihydro-2H-pyrimido[4,5-d]pyrimidin-1-yl]-benzamide
Reaction equation
[CH2:1]([CH3:2])[N:3]([CH2:4][CH2:5][c:6]1[cH:7][c:8]([NH:12][c:13]2[n:14][cH:15][c:16]3[c:17]([n:18]2)[N:19]([c:33]2[cH:34][c:35]([C:36]#[N:37])[cH:38][cH:39][cH:40]2)[C:20](=[O:32])[N:21]([c:24]2[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][cH:29]2)[CH:22]3[CH3:23])[cH:9][cH:10][cH:11]1)[CH2:41][CH3:42].[CH3:55][S:56](=[O:57])[CH3:58].[N:45]#[C:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[Na+:44].[OH-:43].[OH2:59].[OH:53][OH:54]>>[CH2:1]([CH3:2])[N:3]([CH2:4][CH2:5][c:6]1[cH:7][c:8]([NH:12][c:13]2[n:14][cH:15][c:16]3[c:17]([n:18]2)[N:19]([c:33]2[cH:34][c:35]([C:36]([NH2:37])=[O:43])[cH:38][cH:39][cH:40]2)[C:20](=[O:32])[N:21]([c:24]2[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][cH:29]2)[CH:22]3[CH3:23])[cH:9][cH:10][cH:11]1)[CH2:41][CH3:42]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-ffb7b7c2344d419db2d8afc274e4edfb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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