Stannous chloride dihydrate → (5-Bromo-2-methoxyphenyl)hydrazine

HRID 1166238Notes

Reaction equation

HRID 1166238 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[C:4]([NH2:10])[CH:3]=1.[N:11]([O-])=O.[Na+].O.O.Cl[Sn]Cl>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[C:4]([NH:10][NH2:11])[CH:3]=1

Participants

4

Reactant 3

HCID 61436Stannous chloride dihydrateHCID 35853285-Bromo-2-methoxyanilineHCID 23668193Sodium Nitrite

Product 1

HCID 22997636(5-Bromo-2-methoxyphenyl)hydrazineYield 89.1%

Procedure

The title compound was prepared by the general procedure described above for Preparations 2a-i using 4-bromo-2-aminoanisole (9.09 g), NaNO2 (3.45 g), and SnCl2.2H2O (22.6 g). Workup gave 8.7 g (89%) of (5-bromo-2-methoxyphenyl)hydrazine which was used without further purification.

Workup

  1. customThe title compound was prepared by the general procedure

Sources & evidence

ORD record
ord-6b00ce31ef78438d8695ed5dadf13ed8
Source dataset
uspto-grants-2003_09
Patent number
US06613786B2

Reaction notes

Loading…