(2-Methoxy-3-tert-butyl-5-methylphenyl)chlorodimethylsilane → (3-Tert-butyl-2-methoxy-5-methylphenyl)dimethyl(tetramethylcyclopentadienyl)silane

HRID 1166407Notes

Reaction equation

HRID 1166407 reaction equation
[C:1]([C:5]1[C:6]([O:16][CH3:17])=[C:7]([Si:12](Cl)([CH3:14])[CH3:13])[CH:8]=[C:9]([CH3:11])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].[CH3:18][C:19]1[CH:23]([Li])[C:22]([CH3:25])=[C:21]([CH3:26])[C:20]=1[CH3:27]>O1CCCC1>[C:1]([C:5]1[C:6]([O:16][CH3:17])=[C:7]([Si:12]([CH3:14])([CH3:13])[C:22]2([CH3:25])[CH:23]=[C:19]([CH3:18])[C:20]([CH3:27])=[C:21]2[CH3:26])[CH:8]=[C:9]([CH3:11])[CH:10]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 11032947(2-Methoxy-3-tert-butyl-5-methylphenyl)chlorodimethylsilane2×HCID 178506838Lithium tetramethylcyclopentadienide

Product 1

HCID 22555519(3-Tert-butyl-2-methoxy-5-methylphenyl)dimethyl(tetramethylcyclopentadienyl)silane

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a solution consisting of (3-tert-butyl-2-methoxy-5-methylphenyl)chlorodimethylsilane (5.24 g) synthesized in the above described (3) and tetrahydrofuran (50 ml) was added tetramethylcyclopentadienyl lithium (2.73 g) at −35° C., and the mixture was warmed to room temperature during 2 hours and stirred further at room temperature for 10 hours.

Workup

  1. customsynthesized in the

Sources & evidence

ORD record
ord-896ee6c5f3e24bef8d84fda9048bf26c
Source dataset
uspto-grants-2003_09
Patent number
US06613850B1

Reaction notes

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