HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 4-(bromomethyl)naphthalene-1-carboxylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 4-Methyl-1-naphthalenecarboxylic acid | HCID 3014285 | — |
| Catalyst | Azobisisobutyronitrile | HCID 6547 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 4-(bromomethyl)naphthalene-1-carboxylic Acid | HCID 10978350 | 111.8% |
Reaction Steps
A mixture of 4-methylnaphthoic acid (10 g, 54 mmol), N-bromosuccinimide (10 g, 56 mmol) and AIBN (100 mg) in CCl4 (250 mL) was refluxed for 3 hr. The reaction mixture was concentrated and dissolved in ethyl acetate. The organic layer was washed with water, brine and dried over MgSO4. Evaporation of the solvent gave the desired product (16 g, 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06613942B1 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-3fe04e35517b4c8f9524c476bae20b15 |
| Source note | uspto-grants-2003_09 |