反应详情

A mixture of 4-methylnaphthoic acid (10 g, 54 mmol), N-bromosuccinimide (10 g, 56 mmol) and AIBN (100 mg) in CCl4 (250 mL) was refluxed for 3 hr. The reaction mixture was concentrated and dissolved in ethyl acetate. The organic layer was washed with water, brine and dried over MgSO4. Evaporation of the solvent gave the desired product (16 g, 80%).

1. temperaturewas refluxed for 3 hr
2. concentrationThe reaction mixture was concentrated
3. dissolutiondissolved in ethyl acetate
4. washThe organic layer was washed with water, brine
5. dry with materialdried over MgSO4
6. customEvaporation of the solvent