HuagongsheHuagongshe Chemistry Print Report · For research reference only
(5-Methylthiophen-2-yl)boronic acid → N-[5-(5-methyl-2-thienyl)thiophene-2-sulfonyl]pyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (5-Methylthiophen-2-yl)boronic acid | HCID 2734374 | — |
| Reactant | N-(5-bromothiophenesulfonyl)pyrrole | HCID 23445587 | — |
| Product | N-[5-(5-methyl-2-thienyl)thiophene-2-sulfonyl]pyrrole | HCID 22998476 | 72% |
Reaction Steps
N-[5-(5-methyl-2-thienyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 32C from 2-methyl-thiophene-5-boronic acid and N-(5-bromothiophene-2-sulfonyl)pyrrole. Purification by column chromatography using 2% ether/hexanes gave the pure sulfonamide in 72% yield as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06613804B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-dc3069526f0e4e5d9b7ee99f99b47ead |
| Source note | uspto-grants-2003_09 |