反应详情

N-(3,4-dimethyl-5-isoxazolyl)-2-(4-tolylacetyl)thiophene-3-sulfonamide was prepared, as described in Example 93B, by reacting N-(3,4-dimethyl-5-isoxazolyl)-2-[N-methoxy(methylaminocarbonyl)]thiophene-3-sulfonamide with 4-methylbenzylmagnesium chloride, resulting in a 65% yield, m.p. 95-100° C.

1. customresulting in a 65% yield, m.p. 95-100° C.