Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Olanzapine | HCID 135398745 | — |
| Product | HCID 135422991 | HCID 135422991 | — |
Reaction Steps
A 100 g sample of technical grade olanzapine (see Preparation 1) was suspended in water (500 mL). The mixture was stirred at about 25° C. for about 5 days. The product was isolated using vacuum filtration. The product was identified as Dihydrate D olanzapine using x-ray powder analysis. Yield: 100 g. TGA mass loss was 10.2%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06617321B2 |
|---|
| Source dataset | uspto-grants-2003_09 |
|---|
| ORD ID | ord-6f73ab6aa390430086a5488d90ce7136 |
|---|
| Source note | uspto-grants-2003_09 |
|---|
