HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 136360269, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Cholesterol | HCID 5997 | — |
| Reactant | Olanzapine | HCID 135398745 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 136360269 | HCID 136360269 | — |
Reaction Steps
5 g (1%) polyvinyl alcohol (PVA) was added to 500 ml of deionized water. The solution was stirred with a magnetic stir bar and warmed for several hours until all of the PVA dissolved. The mixture was allowed to cool to room temperature. The solution was poured into a square plastic container and stirred with an overhead stirrer at 450 RPM. 1.2 g of olanzapine and 8.8 g of cholesterol was dissolved in 100 ml of methylene chloride. The PVA solution was added and the mixture was stirred for 18 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06617321B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-bb33436eaca34877a51988c41de3532b |
| Source note | uspto-grants-2003_09 |