Ethyl α-(acetylamino)-6-quinolinepropanoate → HCID 21925070, compound

HRID 1167092Notes

Reaction equation

HRID 1167092 reaction equation
C([O:3][C:4](=[O:21])[CH:5]([CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[CH:14]2)[NH:6]C(=O)C)C>Cl>[N:17]1[C:18]2[C:13](=[CH:12][C:11]([CH2:10][CH:5]([C:4]([OH:21])=[O:3])[NH2:6])=[CH:20][CH:19]=2)[CH:14]=[CH:15][CH:16]=1

Participants

3

Reactant 1

HCID 21925091Ethyl α-(acetylamino)-6-quinolinepropanoate

Product 1

HCID 21925070HCID 21925070, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

N-Acetyl β-(6-quinolinyl)-D,L-alanine ethyl ester (728 mg, 2.55 mmol) was heated at reflux in 6N HCl (20 mL). After 20 h, the reaction mixture was concentrated to dryness and the residue was dried in vacuo to provide the title compound, which was used directly in the next reaction.

Workup

  1. concentrationthe reaction mixture was concentrated to dryness
  2. customthe residue was dried in vacuo

Sources & evidence

ORD record
ord-5fda1e3254524becad065386647414b4
Source dataset
uspto-grants-2003_09
Patent number
US06617317B1

Reaction notes

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