Ethanol → HCID 22996561, compound

HRID 1167245Notes

Reaction equation

HRID 1167245 reaction equation
C[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-])=O)=[CH:4][C:3]=1[S:11]([N:14]([CH3:16])[CH3:15])(=[O:13])=[O:12].[CH2:17](O)C>[Pd]>[NH2:8][C:5]1[C:4]([CH3:17])=[C:3]([S:11]([N:14]([CH3:15])[CH3:16])(=[O:12])=[O:13])[CH:2]=[CH:7][CH:6]=1

Participants

4

Reactant 2

HCID 702EthanolHCID 2921148N,N,2-trimethyl-5-nitro-Benzenesulfonamide

Product 1

HCID 22996561HCID 22996561, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

A suspension of 2-methyl-5-nitro(N,N-dimethyl)benzenesulfonamide (2.0 g, 8.20 mmol) and Pd/C (0.30 g) in ethanol (40 mL) was stirred under an H2 balloon for 16 h. The suspension was filtered through Celite and washed with methylene chloride. The filtrate was concentrated to provide 3-amino-2-methyl(N,N-dimethyl) benzenesulfonamide (1.72 g, 98%) as a white solid.

Workup

  1. filtrationThe suspension was filtered through Celite
  2. washwashed with methylene chloride
  3. concentrationThe filtrate was concentrated

Sources & evidence

ORD record
ord-d444b8205b9247d09527fa22a2447c68
Source dataset
uspto-grants-2003_09
Patent number
US06617357B2

Reaction notes

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