Potassium Carbonate → HCID 69982183, compound

Participants

Reaction Steps

3-(4-(4-((3R)-3-Acetoxy-4-trimethylarnmoniobutanoyl)piperazin-1-yl)-3-fluorophenyl)-5(R)-(isoxazol-3-yloxymethyl)oxazolidin-2-one chloride (200 mg, 0.33 mmol) and potassium carbonate (67 mg, 0.49 mmol) were stirred at ambient temperature under nitrogen in MeOH (20 ml) for 5 hours. The mixture was evaporated to dryness, the solid triturated with water, filtered and washed with water (20 ml) to give the desired product (137 mg). MS (ESP): 506 (M+) for C24H33FN5O6;

Provenance & Evidence