Dichloromethane → 4-[6-(5-Methanesulfonyl-2,3-dihydro-indol-1-yl)-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid 1-tert-butoxycarbonyl-pyrrolidin-3-yl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([OH:13])[CH2:11][CH2:12]1.[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH3:33][S:34](=[O:35])(=[O:36])[c:37]1[cH:38][c:39]2[c:43]([cH:44][cH:45]1)[N:42]([c:46]1[n:47][cH:48][n:49][c:50]([O:52][CH:53]3[CH2:54][CH2:55][NH:56][CH2:57][CH2:58]3)[cH:51]1)[CH2:41][CH2:40]2.[Cl:59][CH2:60][Cl:61].[N+:21]([c:22]1[cH:23][cH:24][c:25]([C:28]([Cl:26])=[O:29])[cH:27][cH:30]1)([O-:31])=[O:32]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([O:13][C:28](=[O:29])[N:56]2[CH2:55][CH2:54][CH:53]([O:52][c:50]3[n:49][cH:48][n:47][c:46]([N:42]4[CH2:41][CH2:40][c:39]5[cH:38][c:37]([S:34]([CH3:33])(=[O:35])=[O:36])[cH:45][cH:44][c:43]54)[cH:51]3)[CH2:58][CH2:57]2)[CH2:11][CH2:12]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ef02ee2f8b8040b8bac19a5884b305b7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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