Cyclopropanecarbonyl chloride → HCID 15523513, compound

HRID 1167618Notes

Reaction equation

HRID 1167618 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[O:11][CH2:10][CH:9]([C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([C:18]([F:21])([F:20])[F:19])[CH:13]=3)[N:8]([CH2:22][C:23]#[N:24])[C:7]=2[CH:25]=1.[CH:26]1([C:29](Cl)=[O:30])[CH2:28][CH2:27]1>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[O:11][CH2:10][CH:9]([C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([C:18]([F:20])([F:21])[F:19])[CH:13]=3)[N:8]([CH2:22][CH2:23][NH:24][C:29]([CH:26]3[CH2:28][CH2:27]3)=[O:30])[C:7]=2[CH:25]=1

Participants

3

Reactant 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 22993369HCID 22993369, compound

Product 1

HCID 15523513HCID 15523513, compound

Procedure

The procedure is as in Example 15, starting from the compound obtained in Step A and with the replacement of benzoyl chloride with cyclopropylcarbonyl chloride.

Sources & evidence

ORD record
ord-0d58ef934e5b425d8e7913af2ecece19
Source dataset
uspto-grants-2003_09
Patent number
US06620809B2

Reaction notes

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