HRID1167864

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID19859

4-Bromo-2-chlorophenol

C6H4BrClO

HCID2734326

4-Cyanophenylboronic acid

C7H6BNO2

PRODUCTS

生成物

HCID22994527

3'-Chloro-4'-hydroxy[1,1'-biphenyl]-4-carbonitrile

C13H8ClNO

收率 62%

PROCEDURE

实验过程

4-Cyanophenylboronic acid and 4-bromo-2-chlorophenol were processed as described in Example 167A to provide the title compound (62% yield). 1HNMR (300 MHz, DMSO) δ7.12 (m, 1H), 7.58 (m, 1H), 7.80 (m, 5H); MS (CDI) m/z 247(M+NH4)+.