HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-chlorophenol → 2-Chloro-4-(4-cyanophenyl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-chlorophenol | HCID 19859 | — |
| Reactant | 4-Cyanophenylboronic acid | HCID 2734326 | — |
| Product | 2-Chloro-4-(4-cyanophenyl)phenol | HCID 22994527 | 62% |
Reaction Steps
4-Cyanophenylboronic acid and 4-bromo-2-chlorophenol were processed as described in Example 167A to provide the title compound (62% yield). 1HNMR (300 MHz, DMSO) δ7.12 (m, 1H), 7.58 (m, 1H), 7.80 (m, 5H); MS (CDI) m/z 247(M+NH4)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06620839B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-fa448b29b6974290934f415cfe172cf9 |
| Source note | uspto-grants-2003_09 |