反应详情

温度

50 °C

(S)-4-Benzyloxy-2-(2-benzyloxyethoxy)-1-trityloxy-butane (51 mg, 0.092 mmol) was dissolved in ethyl acetate (3 ml). To the solution was added 5% Pd—C (5.0 mg) and the mixture was stirred under an atmosphere of hydrogen for 15 hours at 50° C. After filtering off catalyst, the filtrate was condensed in vacuo, and the residue was subjected to silica gel chromatography to give (S)-3-(2-hydoxyethoxy)-4-trityloxybutanol (28 mg, yield 78%).

1. filtrationAfter filtering off catalyst
2. customcondensed in vacuo