Thiosemicarbazide → N-[4-[(carbamothioylhydrazinylidene)methyl]-2-fluorophenyl]acetamide
반응식
[C:1]([NH:4][C:5]1[CH:12]=[CH:11][C:8]([CH:9]=O)=[CH:7][C:6]=1[F:13])(=[O:3])[CH3:2].[NH2:14][NH:15][C:16]([NH2:18])=[S:17]>>[C:1]([NH:4][C:5]1[CH:12]=[CH:11][C:8]([CH:9]=[N:14][NH:15][C:16]([NH2:18])=[S:17])=[CH:7][C:6]=1[F:13])(=[O:3])[CH3:2]참가 물질
3
실험 절차
The product was characterized as 4-acetamido-3-fluorobenzaldehyde 15. 4-Acetamido-3-fluorobenzaldehyde 15 reacts with thiosemicarbazide to yield 4-acetamido-3-fluorobenzaldehyde thiosemicarbazone 16. Compound 16 has been tested and shown to be both non-toxic and highly active against M. Tuberculosis.
출처 및 근거
- ORD 기록
- ord-c7d73267abc146a19dd52764e6abc1d8
- 출처 데이터셋
- uspto-grants-2003_09
- 특허 번호
- US06624153B2
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