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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1168255Generated: October 26, 2026

Sodium Iodide → Methyl 5-amino-6-chloro-2-propylimidazo[1,2-a]pyridine-8-carboxylate

https://huagongshe.com/reaction/1168255

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium IodideHCID 5238—
Reactant1-Chloropentan-2-oneHCID 11286463—
ReactantMethyl 2,6-Diamino-5-chloronicotinateHCID 12088100—
ProductMethyl 5-amino-6-chloro-2-propylimidazo[1,2-a]pyridine-8-carboxylateHCID 22992222—

Reaction Steps

The title compounds were prepared according to the procedure described in the step 2 EXAMPLE 1 (METHOD B) using methyl 2,6-diamino-5-chloro-3-pyridinecarboxylate (EXAMPLE 1, METHOD B, Step 1), 1-chloropentane-2-one (Synthesis, 1987, 2, 188-190) and sodium iodide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06624162B2
Source datasetuspto-grants-2003_09
ORD IDord-50c734e175ed49758f7312df5335a31c
Source noteuspto-grants-2003_09