HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Thiophenecarbonyl chloride → HCID 22992426, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Thiophenecarbonyl chloride | HCID 78928 | — |
| Reactant | Methyl 4-(4-aminophenyl)-4-oxobutanoate | HCID 12016833 | — |
| Product | HCID 22992426 | HCID 22992426 | 80.4% |
Reaction Steps
In a manner similar to that described in Example 3, thiophen-2-yl-carbonyl chloride (0.049 g, 0.00033 mol) was allowed to react with 4-(4-amino-phenyl)-4-oxo-butyric acid, methyl ester (0.052 g, 0.00025 mol), and the resulting intermediate was hydrolyzed to give 0.061 g of 4-oxo-4-[4-(thiophen-2-yl-carbonylamino)-phenyl]-butyric acid as a yellow solid; MS-(AP+) MH+304.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06624196B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-c8599b381b0d4850beae0eac49477a4e |
| Source note | uspto-grants-2003_09 |