Triethylamine → HCID 21361363, compound

HRID 1168576Notes

Reaction equation

HRID 1168576 reaction equation
[CH2:1]([C:3]1([CH3:23])[CH:8]([CH3:9])[CH:7]([OH:10])[CH2:6][C:5]([CH2:12][CH3:13])([CH3:11])[N:4]1[O:14][CH:15]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[CH3:16])[CH3:2].[C:24](Cl)(=[O:27])[CH:25]=[CH2:26].C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH2:1]([C:3]1([CH3:23])[CH:8]([CH3:9])[CH:7]([O:10][C:24](=[O:27])[CH:25]=[CH2:26])[CH2:6][C:5]([CH2:12][CH3:13])([CH3:11])[N:4]1[O:14][CH:15]([C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1)[CH3:16])[CH3:2]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 13140Acryloyl chlorideHCID 223418512,6-Diethyl-2,3,6-trimethyl-1-(1-phenylethoxy)piperidin-4-ol

Product 1

HCID 21361363HCID 21361363, compoundYield 870.1%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In analogy to example 1 were reacted 6,36 g (2 mmol) of 2,6-diethyl-2,3,6-trimethyl-1-(1-phenyl-ethoxy)-piperidin-4-ol with 1,81 g (2 mmol) of acryloyl chloride and 2.02 g (2 mmol) of triethylamine in toluene to give 6,5 g (87%) acrylic acid 2,6-di-ethyl-2,3,6-trimethyl-1-(1-phenyl-ethoxy)-piperidin-4-yl ester as yellowish liquid. Elemental analysis calculated for C23H35NO3: C 73,95%; H 9,44%; N 3,75%. Found: C 74,43%; H 9,44%; N 3,91%.

Sources & evidence

ORD record
ord-b4f0980731334d688ce2157764efa813
Source dataset
uspto-grants-2003_09
Patent number
US06624306B2

Reaction notes

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