2,2'-(1-Benzylpiperidine-4,4-diyl)di(ethan-1-ol) → 367282-75-5

HRID 1168694Notes

Reaction equation

HRID 1168694 reaction equation
C([N:8]1[CH2:13][CH2:12][C:11]([CH2:17][CH2:18][OH:19])([CH2:14][CH2:15][OH:16])[CH2:10][CH2:9]1)C1C=CC=CC=1>C(O)C.[Pd]>[OH:19][CH2:18][CH2:17][C:11]1([CH2:14][CH2:15][OH:16])[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1

Participants

4

Reactant 1

HCID 152958272,2'-(1-Benzylpiperidine-4,4-diyl)di(ethan-1-ol)

Product 1

HCID 22989523367282-75-5

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

4,4-bis-(2-hydroxyethyl)piperidine is prepared by catalytic hydrogenation of 1-benzyl-4,4-bis-(2-hydroxyethyl)piperidine in ethanol in the presence of palladium on activated carbon (10% Pd).

Sources & evidence

ORD record
ord-49bb4d4cffe54e10b84f659dc88a1162
Source dataset
uspto-grants-2003_09
Patent number
US06627634B2

Reaction notes

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