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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1168694Generated: October 31, 2026

2,2'-(1-Benzylpiperidine-4,4-diyl)di(ethan-1-ol) → 2-[4-(2-Hydroxyethyl)piperidin-4-yl]ethan-1-ol

https://huagongshe.com/reaction/1168694

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2'-(1-Benzylpiperidine-4,4-diyl)di(ethan-1-ol)HCID 15295827—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product2-[4-(2-Hydroxyethyl)piperidin-4-yl]ethan-1-olHCID 22989523—

Reaction Steps

4,4-bis-(2-hydroxyethyl)piperidine is prepared by catalytic hydrogenation of 1-benzyl-4,4-bis-(2-hydroxyethyl)piperidine in ethanol in the presence of palladium on activated carbon (10% Pd).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06627634B2
Source datasetuspto-grants-2003_09
ORD IDord-49bb4d4cffe54e10b84f659dc88a1162
Source noteuspto-grants-2003_09