HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → Phenylmethyl 4,4-bis(2-hydroxyethyl)-1-piperidinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzyl chloroformate | HCID 10387 | — |
| Reactant | 2-[4-(2-Hydroxyethyl)piperidin-4-yl]ethan-1-ol | HCID 22989523 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Phenylmethyl 4,4-bis(2-hydroxyethyl)-1-piperidinecarboxylate | HCID 22989502 | — |
Reaction Steps
1-benzyloxycarbonyl-4,4-bis-(2-hydroxyethyl)piperidine is prepared by reaction of 4,4-bis-(2-hydroxyethyl)piperidine with benzyl chloroformate in tetrahydrofuran in the presence of triethylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06627634B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-36b52ce730f54afaae321c23661510b3 |
| Source note | uspto-grants-2003_09 |