Hydrochloric Acid → 4-[4-(4,5-Dihydro-5-phenyl-3-isoxazolyl)-2-thiazolyl]piperidine

HRID 116891Notes

Reaction equation

HRID 116891 reaction equation
[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[CH3:36][OH:37].[Cl:38][CH2:39][Cl:40].[ClH:30].[c:1]1([CH:7]2[CH2:8][C:9]([c:12]3[n:13][c:14]([CH:17]4[CH2:18][CH2:19][N:20]([C:23]([O:24][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29])[CH2:21][CH2:22]4)[s:15][cH:16]3)=[N:10][O:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]2[CH2:8][C:9]([c:12]3[n:13][c:14]([CH:17]4[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]4)[s:15][cH:16]3)=[N:10][O:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 887MethanolHCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 666187381,1-Dimethylethyl 4-[4-(4,5-dihydro-5-phenyl-3-isoxazolyl)-2-thiazolyl)-1-piperidinecarboxylate

Product 1

HCID 666184764-[4-(4,5-Dihydro-5-phenyl-3-isoxazolyl)-2-thiazolyl]piperidine

Sources & evidence

ORD record
ord-d43249258e2a49f8a3609f32a5325c28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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