反应详情

A solution of 200 g 2-methyl-3-(4-tert-butylphenyl)-propanal, 280 ml triethylamine and 13.4 g sodium acetate in 800 ml of acetic anhydride was stirred at 120° C. for 5.5 hours. Then the solution was cooled, water was added and the water phase was extracted with hexane. The organic phase was washed with 2N NaOH and water to neutrality, dried and evaporated to dryness. The residue was distilled to yield 185 g of a colorless liquid.

1. temperatureThen the solution was cooled
2. extractionthe water phase was extracted with hexane
3. washThe organic phase was washed with 2N NaOH and water to neutrality
4. customdried
5. customevaporated to dryness
6. distillationThe residue was distilled