反应详情

Into a solution of 4-bromomethyl-7-(4-methylphenyl)-2,3-dihydro-1-benzooxepine (329 mg) in toluene (10 ml) was added triphenylphosphine (393 mg), and the resulting mixture was refluxed for 2 hours. After gradual cooling, the precipitate was collected by filtration and was washed with toluene. The precipitate was dried under reduced pressure to obtain [7-(4-methylphenyl)-2,3-dihydro-1-benzooxepin-4-yl]methyltriphenylphosphonium bromide (549 mg) as a white powder.

1. temperaturethe resulting mixture was refluxed for 2 hours
2. filtrationAfter gradual cooling, the precipitate was collected by filtration
3. washwas washed with toluene
4. customThe precipitate was dried under reduced pressure