HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → HCID 86628156, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | Carbonic acid, bis(1,1-dimethylethyl) ester | HCID 10219638 | — |
| Reactant | HCID 68766582 | HCID 68766582 | — |
| Catalyst | Dichloronickel;hexahydrate | HCID 11791229 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86628156 | HCID 86628156 | — |
Reaction Steps
The [1-methyl-4-(trifluoromethyl)-1H-pyrazol-3-yl]acetonitrile (4.76 mmol, 0.90 g), the di-terbutyl carbonate (9.52 mmol, 2.08 g) and nickel chloride hexahydrate (4.77 mmol, 1.13 g) are added to methanol (10 ml) at room temperature. Sodium borohydride (13.1 mmol, 0.49 g). is added portionwise to the reaction mixture. The reaction mixture is allowed to room temperature and stirred for three hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825068B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-50dd3d71a89d450f9f61cd0575efbd01 |
| Source note | uspto-grants-2010_11 |