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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1169577Generated: November 3, 2026

Stannous chloride dihydrate → HCID 42605101, compound

https://huagongshe.com/reaction/1169577

Reaction equation

Participants

RoleNameHCIDCharge
ReactantStannous chloride dihydrateHCID 61436—
ReactantHCID 59550643HCID 59550643—
SolventEthanolHCID 702—
ProductHCID 42605101HCID 4260510186.1%

Reaction Steps

In analogy to GP 3, reaction of 1.49 g trifluoromethanesulphonic acid 3-cyano-6-cyclopropyl-4-(4-nitro-phenyl)-pyridin-2-yl ester (3.6 mmol, 1 eq.) with 4.1 g tin(II) chloride dihydrate (18.19 mmol, 5 eq.) in 20 mL EtOH yielded 1.2 g of the desired aniline (3.1 mmol, 86% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825114B2
Source datasetuspto-grants-2010_11
ORD IDord-f99dbf05da134c52b91b72a6836e4a16
Source noteuspto-grants-2010_11