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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1169596Generated: October 26, 2026

5-Iodosalicylic acid → Tert-butyl 4-(2-hydroxy-5-iodobenzoyl)piperazine-1-carboxylate

https://huagongshe.com/reaction/1169596

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Iodosalicylic acidHCID 8388—
ReactantTert-butyl 4-(4-chloro-3-cyanobenzoyl)piperazine-1-carboxylateHCID 68766029—
ProductTert-butyl 4-(2-hydroxy-5-iodobenzoyl)piperazine-1-carboxylateHCID 31121968—

Reaction Steps

Performed identical to tert-butyl 4-(4-chloro-3-cyanobenzoyl)piperazine-1-carboxylate in Example 1 except 2-hydroxy-5-iodobenzoic acid was used in place of 3-cyano-4-chlorobenzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825120B2
Source datasetuspto-grants-2010_11
ORD IDord-d0384ed933044b5ca5f5f86bcfb212fd
Source noteuspto-grants-2010_11