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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1169652Generated: November 3, 2026

HCID 86595327, compound → 5,5-Dimethyl-3-{4-[(trifluoromethyl)sulfanyl]phenyl}imidazolidine-2,4-dione

https://huagongshe.com/reaction/1169652

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86595327HCID 86595327—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
Product5,5-Dimethyl-3-{4-[(trifluoromethyl)sulfanyl]phenyl}imidazolidine-2,4-dioneHCID 13268068—

Reaction Conditions

Temperature4 °C

Reaction Steps

30 g of 2-methyl-2-[3-(4-trifluoromethylsulfanylphenyl)ureido]propionate 3 are dissolved in a mixture of 225 ml of 3 N HCl and 230 ml of dioxane, refluxed for 6 hours and, after cooling to 4° C., the product 5,5-dimethyl-3-(4-trifluoromethylsulfanylphenyl)-imidazolidine-2,4-dione is isolated in the form of white crystals (24.14 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825115B2
Source datasetuspto-grants-2010_11
ORD IDord-cc661fa293414183822215cb210bc113
Source noteuspto-grants-2010_11