Acetone → 3-{4-[2-(2-Cyclopropylmethoxy-pyridin-3-yl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-phenyl}-propionic acid methyl ester
Reaction equation
[Br:38][CH2:39][CH:40]1[CH2:41][CH2:42]1.[C:32](=[O:33])([O-:34])[O-:35].[CH3:1][O:2][C:3]([CH2:4][CH2:5][c:6]1[cH:7][cH:8][c:9]([CH2:12][n:13]2[c:14](-[c:24]3[c:25]([OH:30])[n:26][cH:27][cH:28][cH:29]3)[n:15][c:16]3[c:17]2[cH:18][c:19]([F:23])[c:20]([F:22])[cH:21]3)[cH:10][cH:11]1)=[O:31].[CH3:43][C:44](=[O:45])[CH3:46].[Cs+:36].[Cs+:37]>>[CH3:1][O:2][C:3]([CH2:4][CH2:5][c:6]1[cH:7][cH:8][c:9]([CH2:12][n:13]2[c:14](-[c:24]3[c:25]([O:30][CH2:39][CH:40]4[CH2:41][CH2:42]4)[n:26][cH:27][cH:28][cH:29]3)[n:15][c:16]3[c:17]2[cH:18][c:19]([F:23])[c:20]([F:22])[cH:21]3)[cH:10][cH:11]1)=[O:31]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c20d3e8fb5334abf8b7415f9eefe8d1d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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