1H-Imidazole-1-propanamine → 3(2-Chloro-5-thiophen-2-yl-pyrimidine-4-yl)-(3-imidazol-1-yl-propyl)-amine

Participants

Role	Name	HCID	Charge
Reactant	1H-Imidazole-1-propanamine	HCID 78736	—
Reactant	2,4-Dichloro-5-iodopyrimidine	HCID 263438	—
Reactant	4,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane	HCID 10703628	—
Product	3(2-Chloro-5-thiophen-2-yl-pyrimidine-4-yl)-(3-imidazol-1-yl-propyl)-amine	HCID 86615479	—

Reaction Steps

Preparation according to procedures 2 and 3 with the use of 2,4-dichloro-5-iodo-pyrimidine, 3-imidazol-1-yl-propylamine and 4,4,5,5-tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07825128B2
Source dataset	uspto-grants-2010_11
ORD ID	ord-22736563edbc4b00aee5897ed2a605ea
Source note	uspto-grants-2010_11