HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane → 2-Chloro-4-methoxy-5-thiophen-2-yl-pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane | HCID 10703628 | — |
| Reactant | 2-Chloro-5-iodo-4-methoxypyrimidine | HCID 15188888 | — |
| Product | 2-Chloro-4-methoxy-5-thiophen-2-yl-pyrimidine | HCID 58985680 | 54% |
Reaction Steps
Preparation according to procedure 3 with the use of 2-chloro-5-iodo-4-methoxy-pyrimidine and 4,4,5,5-tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane for 36 hrs at 95° C. In this way, a yield of 54% is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825128B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-d8c003faca4b40b4b7143f54e57f06ee |
| Source note | uspto-grants-2010_11 |