HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3,4-Diaminotoluene → 4-Hydroxy-3-(6-methyl-1H-benzoimidazol-2-yl)-1H-[1,7]naphthyridin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3,4-Diaminotoluene | HCID 10332 | — |
| Edukt | 3-[2-(Methoxycarbonyl)acetylamino]pyridine-4-carboxylic acid | HCID 12988781 | — |
| Produkt | 4-Hydroxy-3-(6-methyl-1H-benzoimidazol-2-yl)-1H-[1,7]naphthyridin-2-one | HCID 135518153 | — |
Reaktionsschritte
The title compound was synthesized as described in Example 50 using 3-[2-(methoxycarbonyl)acetylamino]-pyridine-4-carboxylic acid and 4-methyl-1,2-phenylenediamine. The crude product was purified by reversed-phase HPLC (DMSO/5% TFA). LC/MS m/z 293.3 (MH+), Rt 1.99 minutes.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07825132B2 |
| Quelldatensatz | uspto-grants-2010_11 |
| ORD ID | ord-60f72c8ccba74b0aa56142d5bf7e33d6 |
| Quellennotiz | uspto-grants-2010_11 |