反应详情

温度

75 °C

To a stirring solution of chloropropyldimethylvinylsilane (645 g) in ethyl methyl ketone (4.65 L), sodium iodide (1.215 Kg) was added under nitrogen and the mixture heated at 75° C. for 24 hr. The reaction mixture was cooled and added D.M. Water (1.62 L) and separated organic layer. The aqueous layer was re-extracted with ethyl methyl ketone (1.16 L) and the extract combined with the organic layer. The organic layer was dried on sodium sulfate and evaporated to dryness. Orange oil was purified by vacuum distillation to give colourless liquid the title product (540 g).

1. temperatureThe reaction mixture was cooled
2. additionadded D.M
3. customWater (1.62 L) and separated organic layer
4. extractionThe aqueous layer was re-extracted with ethyl methyl ketone (1.16 L)
5. customThe organic layer was dried on sodium sulfate
6. customevaporated to dryness
7. distillationOrange oil was purified by vacuum distillation