HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromopyridine → (2-Methoxy-benzyl)-[5-((E)-2-pyridin-3-yl-vinyl)-quinolin-2-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | (2-Methoxy-benzyl)-(5-vinyl-quinolin-2-yl)-amine | HCID 44218150 | — |
| Product | (2-Methoxy-benzyl)-[5-((E)-2-pyridin-3-yl-vinyl)-quinolin-2-yl]-amine | HCID 68436701 | — |
Reaction Steps
(2-Methoxy-benzyl)-(5-vinyl-quinolin-2-yl)-amine (150 mg, 0.517 mmol) was reacted with 3-bromopyridine (108 mg, 0.688 mmol) as described in example 2 step B. The title compound was obtained as a light brown solid (93 mg, 49%), MS: m/e=368.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825253B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-e1edf8d469684634a5a753d589306366 |
| Source note | uspto-grants-2010_11 |