Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1170124Generated: November 1, 2026

4-Fluorobenzyl bromide → [5-(4-Fluoro-benzyloxy)-quinolin-2-yl]-(5-methyl-furan-2-ylmethyl)-amine

https://huagongshe.com/reaction/1170124

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzyl bromideHCID 68021—
Reactant5-Methyl-2-furylmethylamineHCID 2724683—
Reactant2-chloroquinolin-5-olHCID 135442221—
Product[5-(4-Fluoro-benzyloxy)-quinolin-2-yl]-(5-methyl-furan-2-ylmethyl)-amineHCID 68436831—

Reaction Steps

The title compound, MS: m/e=363.3 (M+H+), was prepared in accordance with the general method of example 63 from 5-hydroxy-2-chloroquinoline (CAS 124467-35-2), 5-methyl-2-furanmethanamine and 4-fluoro-benzyl bromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825253B2
Source datasetuspto-grants-2010_11
ORD IDord-51b285be26aa43a6af0ca4b53b0ce228
Source noteuspto-grants-2010_11