HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitroquinoline → N5-(1H-Indol-4-ylmethyl)-N2-(2-trifluoromethoxy-benzyl)-quinoline-2,5-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitroquinoline | HCID 319251 | — |
| Reactant | Indole-4-carboxaldehyde | HCID 333703 | — |
| Reactant | (2-(Trifluoromethoxy)phenyl)methanamine | HCID 2777251 | — |
| Product | N5-(1H-Indol-4-ylmethyl)-N2-(2-trifluoromethoxy-benzyl)-quinoline-2,5-diamine | HCID 24990474 | — |
Reaction Steps
The title compound, MS: m/e=463.0 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 2-(trifluoromethoxy)benzylamine and 4-formylindole as described in example 26.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825253B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-cd302df24b624d31933c0d4f95840fac |
| Source note | uspto-grants-2010_11 |