1-Bromo-4-fluorobenzene → HCID 24991557, compound

HRID 1170185Notes

Reaction equation

HRID 1170185 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][C:16]1[O:17][C:18]2[C:24]([NH2:25])=[CH:23][CH:22]=[CH:21][C:19]=2[CH:20]=1.Br[C:27]1[CH:32]=[CH:31][C:30]([F:33])=[CH:29][CH:28]=1>>[F:33][C:30]1[CH:31]=[CH:32][C:27]([NH:1][C:4]2[C:5]3[CH:6]=[CH:7][C:8]([NH:25][C:24]4[C:18]5[O:17][C:16]([CH3:15])=[CH:20][C:19]=5[CH:21]=[CH:22][CH:23]=4)=[N:9][C:10]=3[CH:11]=[CH:12][CH:13]=2)=[CH:28][CH:29]=1

Participants

4

Reactant 3

HCID 99931-Bromo-4-fluorobenzeneHCID 3192512-Chloro-5-nitroquinolineHCID 31574852-Methyl-benzofuran-7-ylamine

Product 1

HCID 24991557HCID 24991557, compound

Procedure

The title compound, MS: m/e=384.1 (M+H+), was prepared in accordance with the general method of example 38 from 5-nitro-2-chloroquinoline, (2-methyl-1-benzofuran-7-yl)amine and 1-bromo-4-fluorobenzene.

Sources & evidence

ORD record
ord-5f5764a84f6840de98e36072f6c74433
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

Loading…