HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-amine → N-{2-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)amino]quinolin-5-yl}-N'-(4-fluorophenyl)sulfamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-amine | HCID 91697 | — |
| Reactant | 2-Chloro-5-nitroquinoline | HCID 319251 | — |
| Reactant | 4-Fluoro-phenylsulfamoyl chloride | HCID 21966571 | — |
| Product | N-{2-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)amino]quinolin-5-yl}-N'-(4-fluorophenyl)sulfamide | HCID 68436653 | — |
Reaction Steps
The title compound, MS: m/e=479.0 (M+H+), was prepared in accordance with the general method of example 58 from 5-nitro-2-chloroquinoline, 7-amino-2,3-dihydro-2,2-dimethylbenzofuran (CAS 68298-46-4) and 4-fluoro-phenylsulfamoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825253B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-56d7e3b3032a4529a668dff19336b527 |
| Source note | uspto-grants-2010_11 |